Sonogenetics Welcome to Sonogenetics
What is Sonogenetics?
Sonogenetics is the use of ultrasound to non-invasively manipulate neurons and other cells expressing exogenous protein channels.
Publications from Chalasani lab and collaborators
- Sonogenetic control of mammalian cells using exogenous Transient Receptor Potential A1 channels (Duque et al., 2022)
- Sonogenetics is a non-invasive approach to activating neurons in Caenorhabditis elegans (Ibsen et al., 2015)
- Ultrasound Mediated Cellular Deflection Results in Cellular Depolarization (Vasan et al., 2021)
- Microscale concert hall acoustics to produce uniform ultrasound stimulation for targeted sonogenetics in hsTRPA1-transfected cells (Vasan et al., 2021)
- Two parallel pathways are required for ultrasound-evoked behavioral changes in Caenorhabditis elegans (Magaram et al., 2021)
Meet the Team
Alumni and where they are now:
Uri Magaram: Entrepreneur
Eric Edsinger: Research Scientist, Friday Harbor Labs UW and Whitney Institute
Janki Patel: PhD student at Harvard University
Ahana Chakraborty
Corinne Lee-Kubli: Scientist at DTx Pharma
Yusuf Tufail: Senior scientist at Lundbeck
Marc Duque: PhD student at Harvard University
Jose Mendoza-Lopez: MD-PhD student at the Tri-Institutional MD-PhD Program
Connor Weiss: PhD student at the University of Washington
Rani Shiao: PhD student at the Rockefeller University
Stuart Ibsen: Assistant professor at the Oregon Health and Science University
Collaborations
In order to realize the complete potential of sonogenetics, we have strategically identified individuals, labs and companies that offer technical expertise in various scientific fields. We have established collaborations with key individuals in the fields of materials engineering, transducer design, ion channel biophysics, molecular engineering and neuroscience. We welcome fresh ideas to foster new partnerships that aim to advance sonogenetics for the scientific and clinical community.